The purpose of the map is to compare stage-specific incidence, 1-year, 2-year and 5-year relative survival between Denmark and Schleswig-Holstein.
Incidence: The age-standardized incidence rate is the number of new cases per 100 000 persons per year/period. Standardization is necessary when comparing several populations that differ with respect to age because age has such a powerful influence on the risk of cancer
Relative survival is defined as the ratio of the observed survival in the group of patients to the survival expected in a group of people in the general population, who are similar to the patients with respect to sex, age and calendar time at the time of diagnosis. The relative survival can be interpreted as the probability of patient surviving the cancer in the absence of other causes of death.
Data basis: Included were all registered cancer cases for patients with place of residence in Denmark or Schleswig-Holstein at the time point of diagnosis. Data for this project were obtained from the respective local cancer registry. Data were assigned to a local area, that corresponds to district level in Germany and groups of Municipalities in Denmark, see
this table.
Age Standardized Rates were calculated using World Standard Population. Included were all cases diagnosed in the period 2014-2018.
Relative Survival was calculated using period approach within the period 2014-2018. Follow-up was conducted for 1, 2 and 5 years, respectively. Expected survival with regard to life tables was estimated using Ederer-II formulas. The results were age-standardized with regard to ISCC standards.
All results are stratified by tumour stage. As it might be possible, that the tumour stage for patients without registered stage differs from those patients with registered stage for some reason, the missing stages are to be estimated from other known variables (e.g. time survived, available data for tumour size, and other). To do so, the method of Multiple Imputation was used. Several scenarios of possible unregistered stages were created and the resulting outcomes were combined using Rubins Rule.
FundingThe research was funded by the European regional devellopement fund through the Interreg 5A Deutschland Danmark programme (Grant No. 094-1.1-18). The funding body has no role in the design of the study and collection, analysis and interpretation of the data and the decision to publish.
ImpressumPlease follow this
Link.